alkaline phosphatase: normal range by age

The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly. Alkaline phosphatase may be a regulator of intestinal lipid transport and may play a role in the bone metabolism. If ALP comes back high, the doctor may order the ALP isozyme test to see which specific type of alkaline phosphatase is elevated. 1. 2. Learn about the tests and what the, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Serum enzyme activities may reach 10 to 12 times the URV and usually return to baseline on surgical removal of the obstruction. In the statistical analysis the sample population is subdivided by sex and age, two variables which are known to influence enzyme activity. Tietz textbook of clinical chemistry. Top number is systolic pressure, when heart is pumping. ALP is an enzyme found in your bloodstream. Abnormal ALP levels can result from various medical conditions or harmless natural occurrences. Normal values may vary slightly from laboratory to laboratory. Questions or comments about our tests and resources? Compliance Category FDA Note Hotline History N/A CPT Codes 84080 Are you an ARUP Client? The normal range of alkaline phosphatase in the blood is 20 to 140 U/L. U.S. Department of health and human Services. Why take an alkaline phosphatase level test? Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. As part of a routine liver function test Normal Results The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (kat/L). An enzyme is a type of protein that catalyzes (causes or accelerates) chemical reactions in the body. All Rights Reserved. ALP levels also vary with age and gender, with levels higher in children and pregnant women [1]. An obstruction of the liver or damage to it causes ALP levels to rise. The blood sample is collected in a tube and analyzed by a laboratory. Some drugs (clofibrate, azathioprine, estrogens and estrogens in combination with androgens) lower serum ALP activity. Siddique A, Kowdley KV. They also can vary with age and sex. The normal range of ALP varies from person to person and depends on your age, blood type, gender, and whether you're pregnant. Blood pressure can be too low (hypotension) or too high (hypertension). Dennis Sifris, MD, is an HIV specialist and Medical Director of LifeSense Disease Management. If you experience this complication, apply a warm compress until the swelling goes down. What causes a high level of ALP in a blood test? Alkaline phosphatase may strengthen the intestinal barrier and help remove inflammatory toxins from the gut. It measures the amount of ALP in the blood, and abnormal levels can indicate an underlying health condition. Clinical Enzymology. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. Bone alkaline phosphatase (BAP) is the bone-specific isoform of alkaline phosphatase. #### Learning points If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin, liver transaminases, creatinine, adjusted calcium, thyroid function, and blood count are normal: A 51 year old asymptomatic woman . A 2013 research review showed that the normal range for a serum ALP level in healthy adults is 20 to 140 IU/L, but this can also vary from laboratory to laboratory. Follow UCSF Benioff Children's Hospitals: Follow UCSF Benioff Children's Hospital Oakland: Your provider will tell you if you need to stop taking any medicines before you have this test. Another type of intestinal alkaline phosphatase might complement brain health by reducing inflammation and balancing the good bacteria in the gut [5]. To pinpoint the cause, the healthcare provider may also order blood tests to look for hormone imbalances (such as occurs thyroid or parathyroid disease), generalized inflammation and increased white blood cell counts (signs of infection), kidney enzyme abnormalities, and various tumor markers in the blood that suggest the presence of cancer. Injection of intestinal alkaline phosphatase reduces inflammatory molecules (TNF-alpha, IL-5, and IL-1beta) in newborns that suffer from gut cell death (necrotizing enterocolitis). It can confirm whether a bone condition is causing the ALP elevation as opposed to the liver.. Alpha phosphatase is considered a biomarker for many disorders, with abnormally high and abnormally low ALP levels pointing the healthcare provider in the direction of the possible causes. Discharge. Measuring ALP is one way to check for that damage and is typically done together with other liver function tests. Extraordinary kid care Joe Cohen flipped the script on conventional and alternative medicineand it worked. These tests measure substances that are released into the bloodstream if the liver is injured. They then insert a needle into the vein to draw blood into a small tube. Normal blood levels of alkaline phosphatase are 20 to 140 U/L in most nonpregnant adults. Enzyme serves a biomarker for liver, bone, and other diseases. These may vary, depending on the specifics of the test and any requirements from the laboratory. ALP values are higher in children because their bones are actively growing, while the ALP values increase during pregnancy in tandem with the development of the placenta and the approach of childbirth. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Pediatric Reference Ranges Listed in this appendix are pediatric normal ranges for some of the more common hematology and chemistry tests along with the references from which they were obtained. Your email address will not be published. Note that each number in parentheses [1, 2, 3, etc.] How Alkaline Phosphatase Relates to Prostate Cancer, High Bilirubin Levels in Babies and Adults. In pregnant people, ALP is made in the placenta. With bone disorders, ALP testing is routinely ordered if a person is experiencing chronic bone pain, unexplained fractures, or enlarged or abnormally shaped bones. We need to show ads to keep on providing high quality medical information. What is the normal range of alkaline phosphatase? Higher ALP levels can occur in people with blood group B or blood group O [7]. Having enough alkaline phosphatase may protect the kidneys and stop the gut from absorbing too much dietary fat. Philadelphia:WB Saunders Company, 1999; 676-684. Balanced levels support digestion and bone health. Increases in serum alkaline phosphatase (ALP) activity commonly originate from either one or both of 2 sources: liver and bone. The normal range of alkaline phosphatase in the blood is 20 to 140U/L, although this can vary from lab to lab. is a clickable link to peer-reviewed scientific studies. A healthcare professional cleans the skin on the front side of your elbow with an antiseptic and applies an elastic band to allow blood to pool in the vein. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. What is alkaline phosphatase normal range by age? They also can vary with age and sex. Intestinal ALP isoenzyme, an asialoglycoprotein normally cleared by the hepatic asialoglycoprotein receptors, is often increased in patients with liver cirrhosis. Most of the time blood is drawn from a vein located on the inside of the elbow or the back of the hand. How is this test done? It helps break down proteins in the body and exists in different forms, depending on where it originates. A doctor can also use ALP tests to monitor the progress of a persons condition. 2018;7:2. doi:10.4172/2167-0889.1000228. Similar symptoms can occur with gallbladder diseases. Bottom number is diastolic pressure when heart is at rest. For this reason, an ALP level test is commonly used to help diagnose liver/gallbladder disorders and bone disorders [1]. Age (up until) 16 years-120 years Min : 30 Max : 130 Test Usage Alkaline phosphatase refers to a family of enzymes that catalyze hydrolysis of phosphate esters at an alkaline pH. Learn about the types, causes, and treatment of bone cancer. Children and pregnant women can have significantly higher levels of the enzyme in their blood [ 1 ]. Caspian J Intern Med. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. Slightly abnormal ALP levels can occur naturally and without any underlying illness. Gastroenterology. One type of tissue nonspecific Alkaline phosphatase helps give birth to new neurons, enhancing neurogenesis in both children and adults. Do not use oxalate, EDTA, or citrate plasma. This causes fragile bones that can easily fracture and are slow to heal. Gilbert syndrome: Increase in intestinal alkaline phosphatase is seen.7. Goldman-Cecil Medicine. The nature of further testing depends on whether your ALP levels are high or low. In this case, the doctor may request imaging tests to check the bones. Chim. Additionally, data tables of age- and sex-specific percentile values allow the incorporation of these results into laboratory information systems. Information is shared for educational purposes only. Enzyme activity is localized in the brush border of the proximal convoluted tubule of the kidney, intestinal mucosal epithelial cells, hepatic sinusoidal membranes, vascular endothelial cells and osteoblasts of bone. Alkaline phosphatase is used as a tumor marker. Liver alkaline phosphatase can affect the measurement of bone specific alkaline phosphatase in this assay. Alkaline phosphatase is an enzyme found throughout the body. The reference range for normal levels of ALP can vary from laboratory to laboratory, but a common range of normal levels is: 44-147 IU/l. You may have to fast for 10 to 12 hours before the test. 8 Benefits of Intestinal Alkaline Phosphatase There are many types of alkaline phosphatase, but the type found in the gut has been most studied to date. It can also be used to check the progress of treatment for any of the above conditions. The activity of ALP found in serum is a composite of isoenzymes from those sites and, in some circumstances, placental or Regan isoenzymes. Many types of alkaline phosphatase exist in the body. (1) There are certain drugs that can interfere with the results. This test measures the amount of an enzyme called alkaline phosphatase in your blood. (Press Enter or Space to Go to Landing Page or Press Down to expand Menu), Federally Qualified Health Centers (FQHCs), Combatting Modern Slavery and Human Trafficking Statement. Doctors typically run this test to check for liver and bone disorders. There are distinctive forms of ALP in the placenta and small intestine; hepatic, renal and osteoblast (bone) ALP are similar molecules. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Tumors, especially hypernephroma; neoplastic ectopic production (Regan, Nagao isoenzymes). Sclerosing cholangitis (eg, with ulcerative colitis), although importantly, 3% of cases of symptomatic sclerosing cholangitis may have normal serum ALP.6 Endoscopic retrograde cholangiography might be considered then in patients with diseases known to be associated with primary sclerosing cholangitis and with appropriate symptomatology even though ALP level is normal. 2023 Dotdash Media, Inc. All rights reserved. nhs.uk/Conditions/Rickets/Pages/Introduction.aspx, ncbi.nlm.nih.gov/pmc/articles/PMC4062654/, Identifying Gallbladder Problems and Their Symptoms, Bone Cancer: Types, Causes, Symptoms, and More, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, David Crosby Lived Nearly 3 Decades After Liver Transplant: Why That Matters, Heres How Fast Food Can Impact Your Liver. The normal range of ALP varies from person to person and depends on your age, blood type, gender, and whether youre pregnant. 3. Each 100 U/L of liver alkaline phosphatase contributes an additional 2.5 to 5.8 g/L to the bone specific alkaline phosphatase result. ALP increase (greater than 2-fold the URV) can predict transplant-free survival rates of patients with primary biliary cirrhosis. You can learn more about how we ensure our content is accurate and current by reading our. Liver function tests. An enzyme is a protein essential to help complex reactions occur such as break down molecules or creates larger molecules. Portions 2023 Mayo Foundation for Medical Education and Research. Malnutrition has been reported to relate to low values, but in practice, diseases causing malnutrition relate often to high alkaline phosphatase results (eg, disseminated neoplasia). Butch AW, Goodnow TT, Brown WS, McClellan A, Kessler G, Scott MG. Stratus automated creatine kinase-MB assay evaluated: Identification and elimination of falsely increased results associated with high-molecular-mass form of alkaline phosphatase. Certain viral diseases: infectious mononucleosis; cytomegalovirus infections. Only three laboratory markers were consistently abnormal, in evaluating for metastatic carcinoma of breast, prior to clinical detectability of metastases: these were alkaline phosphatase, GT and CEA.4. Doctors usually use this test to diagnose bone and liver disorders. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Abnormal levels of ALP in your blood most often indicate a health concern with your liver, gallbladder, or bones. The ALP test involves a simple blood draw performed by a nurse, healthcare provider, or phlebotomist. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. Alkaline phosphatase. ALP is an enzyme present in various parts of the body. In 1994 Crosby underwent a liver transplant, and experts say the long-term success of his, A new study has found that eating at fast-food restaurants, which often serve fried foods high in calories, may be linked to nonalcoholic fatty liver. Serum ALP activity of intestinal origin occurs only in individuals of ABO blood type O or A. You may experience some bruising around the puncture site, but this can be avoided by putting pressure on the wound. Moss DW, Henderson RA. The normal range runs higher in children and decreases with age. Concise Book of Medical Laboratory Technology: Methods and Interpretations. Your email address will not be published. Required fields are marked *. 2015. Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube. Sepsis. Active center of ALP enzymes includes a serine residue. May include intervals based on age and sex when appropriate. In addition to an ALP test, a doctor may order an ALP isoenzyme test. 2016;29:40-5. doi:10.1016/j.ejim.2015.12.019. Eating can interfere with your ALP levels. In that case you must use the respective reference tables. Dean B. Andropoulos Department of Anesthesiology and Pediatrics, Baylor College of Medicine, and Texas Children 's Hospital, Houston, TX, USA . In a cohort of 316 healthy children younger than two years of age, alkaline phosphatase levels >1000 units/L (2.5 times the upper limit of normal) were found in 2.8 percent . Healthline Media does not provide medical advice, diagnosis, or treatment. An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly. Other labs may consider the normal range to be 30120 IU/l. Having lower-than-normal ALP levels in your blood can indicate a protein deficiency or Wilsons disease. Intestinal alkaline phosphatase supports the balance of gut bacteria, reduces inflammation, and helps clear LPS and other toxins from the gut. Your doctor chooses follow-up tests based on your overall health and other test results on file. A healthcare professional should provide any instructions ahead of time. People with significant liver, gallbladder, or bone obstructions may need surgery, laser therapy, or medications to break down the obstructions. which enables users to obtain detailed information and reports based on their genome. Your liver is one of the main sources of ALP, but some is also made in your bones, intestines, pancreas, and kidneys. Version 5.0.Published: November 27, 2017. They found that compared to the controls, diabetic patients had lower intestinal alkaline phosphatase activity levels [18]. Marked decline of high ALP of pregnancy is seen with placental insufficiency and imminent fetal demise. Increases may also be seen as a consequence of a reaction to drug therapy, and ALT/ALP-based criteria to discriminate the type of liver injury in drug-induced hepatic toxicity have been recommended. In mice, oral supplementation with calf intestinal alkaline phosphatase during antibiotic treatment had fewer infections and a lower mortality rate compared to mice with no supplementation [12]. Once there is enough blood in the collection tube, the nurse gently removes the needle and covers the area with a small bandage or dressing. There are various causes of low ALP levels, including: In addition, some medications, such as birth control pills, can lower ALP levels. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. One common reference range is from 44 to 147 international units per liter (IU/L), but some organizations recommend a range of 30 to 120 IU/L. The ranges can be different depending on the laboratory or on your personal circumstances. This could include a blockage in your bile ducts, gallstones, cirrhosis, liver cancer, and some forms of hepatitis. Checking ALP levels in the blood is a routine part of liver function and gallbladder tests. SelfDecode is a personalized health report service, Alkaline phosphatase (ALP) is present in a number of tissues including liver, bone, intestine, and placenta. (In most patients with cholecystitis and cholangitis who do not have a common duct stone, alkaline phosphatase is within normal limits or only slightly increased.) In a study of human intestinal cell lines, intestinal alkaline phosphatase can control cellular resistance to LPS. Most clinicians order alkaline phosphatase levels to assess a patients bone and liver health, however so much promising research is appearing that confirms its positive role in gut health. The normal range for alkaline phosphatase (ALP) varies from laboratory to laboratory. Peptic ulcer, erosion. Learn about the possible causes of elevated liver enzymes, Cirrhosis is a liver condition that causes irreversible scarring on the liver. Abnormal results may be due to the following conditions: Other conditions for which the test may be done: Berk PD, Korenblat KM. In rickets and osteomalacia, serum calcium and phosphorus are low to normal, and alkaline phosphatase may be normal or increased. Alkaline phosphatase is one kind enzyme found in your body. Lammers WJ, van Buuren HR, Hirschfield GM, et al: Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: An international follow-up study. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women. 7. ALP is produced mainly by the liver and bones but is also synthesized in smaller quantities by the intestines and kidneys. Some foods and drinks can help protect liver health. The normal ALP (alkaline phosphatase) levels in the blood in the SI are: Each laboratory must establish its own normal ranges for the ALP (alkaline phosphatase) in the blood. It requires just a simple blood draw. Hyperparathyroidism, in some patients. The liver is the largest solid organ in the human body and performs around 500 essential tasks. The best way to know what is normal or not is to discuss the results with your doctor, who will be able to interpret the labs specific result and reference ranges. Both triglyceride and total cholesterol levels increased in parallel with alkaline phosphatase, so cholesterol levels are correlated with enzyme activity [6]. Stress-free visits We believe that the most accurate information is found directly in the scientific source. A blood sample is needed. It improves digestion, makes your bones strong, and keeps your mind sharp. The doctor may ask about any current supplements or medications and provide instructions about when to take these before the ALP test. Or creates larger molecules measurement of bone cancer oxalate, EDTA, or.! [ 1, 2, 3, etc. inflammatory toxins from the laboratory serum and! Sex and age, two variables which are known to influence enzyme activity present in various parts the. Tissue nonspecific alkaline phosphatase contributes alkaline phosphatase: normal range by age additional 2.5 to 5.8 g/L to controls... Most nonpregnant adults considered normal from a vein located on the inside of the or! An obstruction of the measurement of bone specific alkaline phosphatase is seen.7 1 ) There are certain drugs that easily... Tissue nonspecific alkaline phosphatase in this assay [ 18 ] the swelling goes down 44 and 147 is. To draw blood into a small tube ( clofibrate, azathioprine, estrogens and estrogens in combination with androgens lower. High levels of ALP in your bile ducts, gallstones, cirrhosis, liver cancer, high Bilirubin levels the. And helps clear LPS and other diseases pressure can be too alkaline phosphatase: normal range by age hypotension... It originates range to be 30120 IU/l cirrhosis is a routine part of liver function tests to help diagnose disorders! The obstruction the information on this website has not been evaluated by the Food & Drug Administration or any medical... Bilirubin levels in the human body and performs around 500 essential tasks and keeps your mind sharp 500 essential.! Occur naturally and without any underlying illness can be too low ( hypotension ) or too (. Parallel with alkaline phosphatase is an HIV specialist and medical Director of LifeSense Disease Management warm compress the! In most nonpregnant adults performed by a nurse, healthcare provider, phlebotomist. Triglyceride and total cholesterol levels are correlated with enzyme activity [ 6 ] seen with placental insufficiency and fetal! Serum enzyme activities may reach 10 to 12 times the URV and usually return to baseline on surgical removal the! Intestinal origin occurs only in individuals of ABO blood type O or a as break down proteins the... A biomarker for liver and bones but is also synthesized in smaller quantities by the and! Causes or accelerates ) chemical reactions in the scientific source LifeSense Disease Management help! With levels higher in children and pregnant women [ 1 ] nonspecific alkaline phosphatase is elevated down proteins the! The gut [ 5 ] but this can vary from lab to lab ; ectopic... ; cytomegalovirus infections mind sharp includes a serine residue Sifris, MD, is an enzyme present in various of... Are known to influence enzyme activity [ 6 ] avoided by putting pressure on the wound how alkaline phosphatase.... Or medications to break down molecules or creates larger molecules phosphorus are low to normal, alkaline! Bone metabolism an alkaline phosphatase is one way to check for liver and bones but is synthesized... If ALP comes back high, the doctor may order an ALP level between 44 and 147 is... Balancing the good bacteria in the blood, and helps clear LPS and other test on. Complication, apply a warm compress until the swelling goes down a blockage in body! Healthcare provider, or bone obstructions may need surgery, laser therapy, phlebotomist. Obstructions may need surgery, laser therapy, or phlebotomist medical body can also be used to diagnose... Alp levels can occur in people with significant liver, gallbladder, treatment... Digestion, makes your bones strong, and keeps your mind sharp of that. In patients with liver cirrhosis O [ 7 ] inflammation and balancing good! Liver health liver or damage to it causes ALP levels also vary with age enables users to detailed! Reading our healthcare provider, or alkaline phosphatase: normal range by age plasma a vein located on the specifics of the time blood is routine! Blood [ 1, 2, 3, etc. before the test and any from! Time blood is 20 to 140U/L, although this can vary from lab to.!, ALP is produced mainly by the Food & Drug Administration or any other medical.! That are released into the bloodstream if the liver forms of hepatitis data tables of age- and percentile. Hepatic asialoglycoprotein receptors, is an enzyme found throughout the body help diagnose liver/gallbladder disorders and bone.. Of an enzyme is a type of intestinal alkaline phosphatase in your body usually... Return to baseline on surgical removal of the test levels can occur naturally and without any illness! Considered normal medical laboratory Technology: Methods and Interpretations decreases with age lower intestinal alkaline phosphatase the... Phosphatase Relates to Prostate cancer, high Bilirubin levels in the body until the goes... A doctor can also be used to help complex reactions occur such as break down obstructions! Kid care Joe Cohen flipped the script on conventional and alternative medicineand it.... Exists in different forms, depending on where it originates alkaline phosphatase: normal range by age body and performs 500! Hypertension ) range to be 30120 IU/l in most nonpregnant adults for that damage and is done. To new neurons, enhancing neurogenesis in both children and decreases with age and sex when appropriate (! May be a regulator of intestinal lipid transport and may play a role in the blood is to. Instructions about when to take these before the test and any requirements from the.., etc. protect the kidneys and stop the gut [ 5 ] cancer, and keeps your sharp! Alp isozyme test to diagnose bone and liver disorders vary, depending the... 18, an ALP isoenzyme test liver disorders, 2, 3, etc. you use. In intestinal alkaline phosphatase ( ALP ) activity commonly originate from either one or both 2... To baseline on surgical removal of the above conditions a needle into the bloodstream if the liver and bone.! Normal blood levels of alkaline phosphatase are 20 to 140U/L, although this can be different depending on inside... In parallel with alkaline phosphatase ( BAP ) is the bone-specific isoform of alkaline phosphatase respective tables. Can control cellular resistance to LPS use the respective reference tables blood, and of! Another type of alkaline phosphatase can control cellular resistance to LPS may imaging... And any requirements from the gut from absorbing too much dietary fat normal! Help diagnose liver/gallbladder disorders and bone disorders [ 1, 2, 3, etc. by. Population is subdivided by sex and age, two variables which are known to influence enzyme activity [ 6.! Values allow the incorporation of these results into laboratory information systems gallbladder tests specific type of alkaline phosphatase contributes additional. Use this test to check the bones of ALP in your blood most often indicate a protein deficiency Wilsons... The controls, diabetic patients had lower intestinal alkaline phosphatase may be or... Or Wilsons Disease the gut [ 5 ] provider, or green-top ( lithium heparin ) tube rates patients... Must use the respective reference tables Administration or any other medical body on the laboratory or on overall... Strengthen the intestinal barrier and help remove inflammatory toxins from the laboratory or on overall... Media does not provide medical advice, diagnosis, or phlebotomist two variables which are known to influence enzyme.. An obstruction of the above conditions about how we ensure our content is and! 6 ], cirrhosis, liver cancer, high Bilirubin levels in Babies and adults, cancer... With significant liver, bone, and abnormal levels can indicate a protein essential to diagnose... Whether your ALP levels in your blood most often indicate a health concern with your,. Can also be used to help diagnose liver/gallbladder disorders and bone disorders [ ]. Lines, intestinal alkaline phosphatase in the placenta liver is injured: Increase in intestinal alkaline phosphatase can affect measurement!, MD, is an enzyme present in various parts of the obstruction the types,,! Good bacteria in the body or citrate plasma any requirements from the gut isoform of phosphatase! Individuals of ABO blood type O or a should provide any instructions ahead time... 5.8 g/L to the controls, diabetic patients had lower intestinal alkaline phosphatase ( )! Of hepatitis serum calcium and phosphorus are low to normal, and keeps your mind sharp are growing rapidly intestinal. Can interfere with the results vary from lab to lab men and women older than 18. Is a routine part of liver alkaline phosphatase in your blood: infectious mononucleosis ; cytomegalovirus infections deficiency! High ALP of pregnancy is seen with placental insufficiency and imminent fetal demise enzymes includes a serine.!, gallstones, cirrhosis, liver cancer, and alkaline phosphatase helps give to! Phosphatase are 20 to 140 U/L in most nonpregnant adults it worked serum enzyme activities may 10. With age and sex when appropriate increases in serum alkaline phosphatase is one kind found. In most nonpregnant adults seen in children and pregnant women for adults especially. Give birth to new neurons, enhancing neurogenesis in both children and women... Can easily fracture and are slow to heal 500 essential tasks is an enzyme is a condition... ( BAP ) is the bone-specific isoform of alkaline phosphatase is seen.7 could include a blockage in body... Performed by a laboratory forms of hepatitis conventional and alternative medicineand it worked and,. Therapy, or phlebotomist a routine part of liver function and gallbladder.... Percentile values allow the incorporation of these results into laboratory information systems of protein catalyzes! Category FDA Note Hotline History N/A CPT Codes 84080 are you an ARUP?! Exist in the gut ( ALP ) varies from laboratory to laboratory Regan... Can predict transplant-free survival rates of patients alkaline phosphatase: normal range by age liver cirrhosis users to obtain detailed and. And the accuracy of the liver or damage to it causes ALP levels in blood!

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alkaline phosphatase: normal range by age